Description | Adlercreutizia hattorii is a Gram-positive, rod-shaped bacterium that thrives in the anaerobic environment of the human gut. This microbe is classified as asaccharolytic, meaning it does not ferment sugars to generate energy, which is reflected in its metabolic pathways. Notably, *A. hattorii* is unable to convert daidzein, an isoflavonoid found in various plants, into equol due to the absence of specific equol-biosynthesis genes. Furthermore, it does not produce O-desmethylangolensin, a metabolite linked to various health benefits in humans.The proteome of *A. hattorii* suggests that it shares core traits with other members of the Coriobacteriaceae family, indicating a specialized adaptation to the gut microbiome. This association points to its potential role in human digestion and metabolic processes, although its precise contributions and interactions within the gut ecosystem remain to be fully elucidated. Its presence can be influenced by dietary patterns and overall gut health, showcasing the dynamic nature of microbiota composition. Additionally, *Adlercreutizia hattorii* is of particular interest for researchers studying the gut microbiome due to its unique metabolic capabilities. The inability to convert daidzein to equol might suggest specific roles in dietary interactions, potentially implicating it in the modulation of gut flora and overall gut health. This microbe could also serve as an indicator of dysbiosis or an imbalance in the gut microbiome, making it a relevant subject for further investigation in the context of human health and disease. |
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