| Description | Blautia hydrogenotrophica is a Gram-positive, rod-shaped bacterium that thrives in a mesophilic environment, preferring temperatures between 25-40°C. As a hydrogenotroph, it relies on hydrogen as its primary energy source, which is produced through the fermentation of simple sugars. Energy production occurs through the process of fermentation, where the bacterium anaerobically converts sugars into lactic acid, succinic acid, and other byproducts. As a resident of the human gut microbiome, B. hydrogenotrophica colonizes various body sites, including the large intestine, small intestine, and oral cavity, where it plays a crucial role in the breakdown of complex carbohydrates and the production of short-chain fatty acids. The bacterium is a strict anaerobe, meaning it requires the absence of oxygen to grow and thrive, and is often found in environments with low oxygen levels. Blautia hydrogenotrophica is a chemoorganoheterotroph, utilizing organic compounds as both its energy source and carbon source. It produces ATP through substrate-level phosphorylation, a process that involves the conversion of one high-energy molecule to another without the direct involvement of oxygen. This microbe has been found to be present in various species, including humans, mice, and other mammals, where it contributes to the maintenance of gut health and the modulation of the immune system. Moreover, B. hydrogenotrophica has been linked to several diseases, including inflammatory bowel disease and gastrointestinal disorders. Notably, Blautia hydrogenotrophica has been found to be a key player in the human gut microbiome's response to diet. Studies have shown that the bacterium's abundance and activity are influenced by the types and amounts of carbohydrates consumed, with a diet rich in fiber promoting its growth and activity. This highlights the complex interactions between the host and its microbiome, and the importance of understanding the relationships between diet, gut health, and overall well-being. |
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