MiMeDB: Showing metabocard for Adenosyl cobyrinate diamide (MMDBc0048053)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2022-04-29 21:47:00 UTC

Update Date

2025-01-15 18:22:31 UTC

Metabolite ID

MMDBc0048053

Metabolite Identification

Common Name

Adenosyl cobyrinate diamide

Description

Adenosyl cobyrinic acid a,c diamide is an intermediate in the metabolism of Porphyrin and chlorophyll. It is a substrate for Cob(I)yrinic acid a,c-diamide adenosyltransferase (mitochondrial).

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Molecular Formula

C₅₅H₇₃CoN₁₁O₁₅

Average Mass

1187.166

Monoisotopic Mass

1186.461961

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C45H62N6O12.C10H12N5O3.Co/c1-21-36-24(10-13-32(56)57)41(3,4)28(49-36)18-27-23(9-12-31(54)55)43(6,19-29(46)52)39(48-27)22(2)37-25(11-14-33(58)59)44(7,20-30(47)53)45(8,51-37)40-26(17-35(62)63)42(5,38(21)50-40)16-15-34(60)61;1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15;/h18,23-26,40H,9-17,19-20H2,1-8H3,(H10,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63);2-4,6-7,10,16-17H,1H2,(H2,11,12,13);/q;;+2/p-1/t23-,24-,25-,26+,40-,42-,43+,44+,45+;4-,6-,7-,10-;/m11./s1

InChI Key

OCNLJCZKGHKJGF-NQYRMHKHSA-M

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Extracellular
Membrane

Biospecimen Locations

Feces

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species
MMDBp0192624	Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial	Enzyme	Q96EY8	Homo sapiens

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0006900	Adenosyl cobyrinate diamide	Adenosyl cobyrinate a,c diamide	Not Available		VMH	30371894
MMDBr0006919	Cob(I)yrinate a,c diamide	Adenosyl cobyrinate diamide	Not Available		VMH	30371894

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria/Eubacteria	Proteobacteria	124	Human feces; Human ; Human sputum; Human unknown; Human pleural fluid plaque; Human feces; pleural fluid plaque; bal; Human stool	Metabolic reconstruction
Bacteria/Eubacteria	Verrucomicrobia	1	Human ; Human feces	Metabolic reconstruction
Bacteria/Eubacteria	Firmicutes	219	Human feces; Human ; Pig ; Human stool; Human saliva	Metabolic reconstruction
Bacteria/Eubacteria	Bacteroidetes	118	Human feces; Human ; Human stool; Human urine; Human appendix biopsy; Human saliva; Human gastric fluid; Human subgingival plaque	Metabolic reconstruction
Bacteria	Actinobacteria	10	Human feces; Human	Metabolic reconstruction
Archaea	Thaumarchaeota	1		Metabolic reconstruction
Bacteria/Eubacteria	Fusobacteria	20	Human feces; Human	Metabolic reconstruction
Bacteria/Eubacteria	Synergistetes	3	Human feces	Metabolic reconstruction
Bacteria	Firmicutes	20	Human feces; Human ; Pig ; Human stool; Human saliva	Metabolic reconstruction
Bacteria/Eubacteria	Actinobacteria	23	Human feces; Human	Metabolic reconstruction
Bacteria	Proteobacteria	6	Human feces; Human ; Human sputum; Human unknown; Human pleural fluid plaque; Human feces; pleural fluid plaque; bal; Human stool	Metabolic reconstruction
Archaea	Euryarchaeota	5		Metabolic reconstruction
Eukaryota/Fungi	Ascomycota	1		Metabolic reconstruction
Archaea	Crenarchaeota	1		Metabolic reconstruction
Bacteria/Eubacteria	Planctomycetes	1	Human feces	Metabolic reconstruction
Bacteria	Synergistetes	1	Human feces	Metabolic reconstruction

Exposure Sources

Source Type	Activity	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified									HMDB

External Links

Not Available

References

Synthesis Reference

Not Available

General References

Noronha A, Modamio J, Jarosz Y, Guerard E, Sompairac N, Preciat G, Danielsdottir AD, Krecke M, Merten D, Haraldsdottir HS, Heinken A, Heirendt L, Magnusdottir S, Ravcheev DA, Sahoo S, Gawron P, Friscioni L, Garcia B, Prendergast M, Puente A, Rodrigues M, Roy A, Rouquaya M, Wiltgen L, Zagare A, John E, Krueger M, Kuperstein I, Zinovyev A, Schneider R, Fleming RMT, Thiele I: The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992. [PubMed:30371894 ]

Showing metabocard for Adenosyl cobyrinate diamide (MMDBc0048053)

MOL for #<Metabolite:0x00007f3e34675a60>

3D MOL for #<Metabolite:0x00007f3e34675a60>

3D SDF for #<Metabolite:0x00007f3e34675a60>

3D-SDF for #<Metabolite:0x00007f3e34675a60>

PDB for #<Metabolite:0x00007f3e34675a60>

3D PDB for #<Metabolite:0x00007f3e34675a60>

SMILES for #<Metabolite:0x00007f3e34675a60>

INCHI for #<Metabolite:0x00007f3e34675a60>

Structure for #<Metabolite:0x00007f3e34675a60>

3D Structure for #<Metabolite:0x00007f3e34675a60>