Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-23 23:16:33 UTC
Update Date2024-10-11 03:35:39 UTC
Metabolite IDMMDBc0047933
Metabolite Identification
Common NameFolinic acid
DescriptionFolinic acid (CAS: 58-05-9), also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate (a chemotherapy agent and immune system suppressant) and pyrimethamine (Wikipedia). Folinic acid is the active metabolite of folic acid. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid.
Structure
SynonymsNot Available
Molecular FormulaC20H23N7O7
Average Mass473.4393
Monoisotopic Mass473.165896125
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry Number68538-85-2
SMILESNot Available
InChI Identifier
InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1
InChI KeyVVIAGPKUTFNRDU-STQMWFEESA-N