MiMeDB: Showing metabocard for (6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin (MMDBc0033199)

Record Information

Version

2.0

Status

Detected and Quantified

Creation Date

2021-11-19 04:38:46 UTC

Update Date

2025-01-15 23:51:13 UTC

Metabolite ID

MMDBc0033199

Metabolite Identification

Common Name

(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin

Description

(6R)-6-(L-Erythro-1,2-Dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin is catalyzed by 4a-hydroxytetrahydrobiopterin dehydratase to form 6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin

Structure

MOL SDF PDB SMILES InChI


  Mrv0541 02241222492D          

 16 17  0  0  1  0            999 V2000
   -0.7145   -2.8875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -2.4750    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.7145   -2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579    0.0000    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5724   -1.2375    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8579   -2.4750    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  1  0  0  0
  2  4  1  0  0  0  0
  4  5  1  0  0  0  0
  6  4  1  1  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10 11  1  0  0  0  0
 11 12  2  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 13 15  2  0  0  0  0
  9 15  1  0  0  0  0
 15 16  1  0  0  0  0
  6 16  1  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0033199

> <DATABASE_NAME>
MIME

> <SMILES>
C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O)=C2N1

> <INCHI_IDENTIFIER>
InChI=1S/C9H14N4O3/c1-4(14)7(15)5-2-10-8-6(13-5)9(16)12-3-11-8/h3-5,7,13-15H,2H2,1H3,(H2,10,11,12,16)/t4-,5+,7?/m0/s1

> <INCHI_KEY>
XHZMOKNFPZDZBZ-YQGMFIQUSA-N

> <FORMULA>
C9H14N4O3

> <MOLECULAR_WEIGHT>
226.2325

> <EXACT_MASS>
226.106590334

> <JCHEM_ACCEPTOR_COUNT>
7

> <JCHEM_AVERAGE_POLARIZABILITY>
22.015641123936096

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
5

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S)-1-[(6R)-4-hydroxy-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol

> <ALOGPS_LOGP>
-0.33

> <JCHEM_LOGP>
-1.1349783536666667

> <ALOGPS_LOGS>
-1.42

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
13.899245874945983

> <JCHEM_PKA_STRONGEST_ACIDIC>
12.867526394034464

> <JCHEM_PKA_STRONGEST_BASIC>
1.276318374987519

> <JCHEM_POLAR_SURFACE_AREA>
110.53

> <JCHEM_REFRACTIVITY>
60.092600000000004

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
8.55e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2S)-1-[(6R)-4-hydroxy-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-FEB-12         0                                  
HETATM    1  C   UNK     0      -1.334  -5.390   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       0.000  -4.620   0.000  0.00  0.00           C+0
HETATM    3  O   UNK     0       1.334  -5.390   0.000  0.00  0.00           O+0
HETATM    4  C   UNK     0       0.000  -3.080   0.000  0.00  0.00           C+0
HETATM    5  O   UNK     0      -1.334  -2.310   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0       1.334  -2.310   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM    8  N   UNK     0       2.667   0.000   0.000  0.00  0.00           N+0
HETATM    9  C   UNK     0       4.001  -0.770   0.000  0.00  0.00           C+0
HETATM   10  N   UNK     0       5.335   0.000   0.000  0.00  0.00           N+0
HETATM   11  C   UNK     0       6.668  -0.770   0.000  0.00  0.00           C+0
HETATM   12  N   UNK     0       6.668  -2.310   0.000  0.00  0.00           N+0
HETATM   13  C   UNK     0       5.335  -3.080   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0       5.335  -4.620   0.000  0.00  0.00           O+0
HETATM   15  C   UNK     0       4.001  -2.310   0.000  0.00  0.00           C+0
HETATM   16  N   UNK     0       2.667  -3.080   0.000  0.00  0.00           N+0
CONECT    1    2                                                            
CONECT    2    1    3    4                                                  
CONECT    3    2                                                            
CONECT    4    2    5    6                                                  
CONECT    5    4                                                            
CONECT    6    4    7   16                                                  
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10   15                                                  
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14   15                                                  
CONECT   14   13                                                            
CONECT   15   13    9   16                                                  
CONECT   16   15    6                                                       
MASTER        0    0    0    0    0    0    0    0   16    0   34    0
END

Synonyms

Not Available

Molecular Formula

C₉H₁₄N₄O₃

Average Mass

226.2325

Monoisotopic Mass

226.106590334

IUPAC Name

(2S)-1-[(6R)-4-hydroxy-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol

Traditional Name

(2S)-1-[(6R)-4-hydroxy-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol

CAS Registry Number

Not Available

SMILES

C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O)=C2N1

InChI Identifier

InChI=1S/C9H14N4O3/c1-4(14)7(15)5-2-10-8-6(13-5)9(16)12-3-11-8/h3-5,7,13-15H,2H2,1H3,(H2,10,11,12,16)/t4-,5+,7?/m0/s1

InChI Key

XHZMOKNFPZDZBZ-YQGMFIQUSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pteridines and derivatives. These are polycyclic aromatic compounds containing a pteridine moiety, which consists of a pyrimidine fused to a pyrazine ring to form pyrimido(4,5-b)pyrazine.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Pteridines and derivatives

Sub Class

Not Available

Direct Parent

Pteridines and derivatives

Alternative Parents

Substituents

Pteridine
Hydroxypyrimidine
Secondary aliphatic/aromatic amine
Imidolactam
Pyrimidine
Heteroaromatic compound
1,3-aminoalcohol
Secondary alcohol
1,2-diol
1,2-aminoalcohol
Azacycle
Secondary amine
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Amine
Alcohol
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Property	Value	Source
Water Solubility	8.55 g/L	ALOGPS
logP	-0.33	ALOGPS
logP	-1.1	ChemAxon
logS	-1.4	ALOGPS
pKa (Strongest Acidic)	12.87	ChemAxon
pKa (Strongest Basic)	1.28	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	7	ChemAxon
Hydrogen Donor Count	5	ChemAxon
Polar Surface Area	110.53 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	60.09 m³·mol⁻¹	ChemAxon
Polarizability	22.02 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-0udi-4900000000-dfcd5c5f53e526480c02	2016-09-22	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0kdi-0190000000-273028e7de9f27473bd3	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0zi0-0950000000-1e0b4ea90980ce22076d	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0ff0-2900000000-2c91ec8dc90521499b55	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-004i-0490000000-59bb40efa9129a557fd4	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-0059-0930000000-75eb512594c1a0262729	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-0f6x-9400000000-69c194d9d9f13edbf024	2016-09-12	View Spectrum

Chromatographic Retention Times and Retention Indices

Retention Times

Chromatography Type	Technique	Column	Deposition Date	Retention Time (s)
Liquid Chromatography	HILIC	Waters Acquity UPLC-BEH Amide column (eluted)	2025-10-24	395.8
Liquid Chromatography	HILIC	Accucore 150 Amide HILIC (eluted)	2025-10-24	387.2
Liquid Chromatography	Reversed-phase	Hypersil Gold 1.9 µm C18 (eluted)	2025-10-24	47.3
Liquid Chromatography	Reversed-phase	Agilent Zorbax Eclipse Plus C18 (2.1 mm x 150 mm, 3.5 um) (eluted)	2025-10-24	236.5
Liquid Chromatography	Reversed-phase	XBridge C18 3.5u 2.1x50 mm (eluted)	2025-10-24	295.5
Liquid Chromatography	Reversed-phase	Ascentis Express C18 (void)	2025-10-24	225.8
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	508.1
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (void)	2025-10-24	783.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC (eluted)	2025-10-24	519.2
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	135.2
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (eluted)	2025-10-24	497.5
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	154.6
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	41.7
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (eluted)	2025-10-24	249.3
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (eluted)	2025-10-24	582.1
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	49.8
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	174.9
Liquid Chromatography	Reversed-phase	Kinetex Core-Shell C18 2.6 um, 3.0 x 100 mm, Phenomenex (eluted)	2025-10-24	616.6
Liquid Chromatography	Reversed-phase	Waters Atlantis T3 (2.1 x 150 mm, 5 um) (eluted)	2025-10-24	529.3

Retention Indices

Chromatography Type	Peak Label	SMILES	Stationary Phase	Deposition Date	Retention Index
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_1	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CNC2=NC=NC(O)=C2N1	standard non polar	2025-10-24	2398.32
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_2	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O)=C2N1	standard non polar	2025-10-24	1807.22
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_3	C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1	standard non polar	2025-10-24	2119.88
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_4	C[C@H](O)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1	standard non polar	2025-10-24	1618.86
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_5	C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	1402.17
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_6	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O)=C2N1	standard non polar	2025-10-24	2541.12
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_7	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1	standard non polar	2025-10-24	1692.73
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_8	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1	standard non polar	2025-10-24	1778.53
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_9	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CNC2=NC=NC(O)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	1782.72
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_10	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1	standard non polar	2025-10-24	2350.35
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_11	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1	standard non polar	2025-10-24	2056.19
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_12	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	2243.07
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_13	C[C@H](O)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1	standard non polar	2025-10-24	2003.66
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_14	C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	2059.01
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_15	C[C@H](O)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	1864.8
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_16	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1	standard non polar	2025-10-24	1496.49
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_17	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1	standard non polar	2025-10-24	1732.82
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_18	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	2114.91
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_19	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1	standard non polar	2025-10-24	2943.4
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_20	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	2321.99
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_21	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	1559.57
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_22	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1	standard non polar	2025-10-24	2338.77
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_23	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	2031.52
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_24	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	1766.16
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_25	C[C@H](O)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	2503.16
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_26	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1	standard non polar	2025-10-24	1933.08
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_27	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	1782.79
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_28	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	1676.19
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_29	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	1538.57
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_30	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	2124.24
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_31	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard non polar	2025-10-24	2151.27
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_1	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CNC2=NC=NC(O)=C2N1	standard polar	2025-10-24	2055.04
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_2	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O)=C2N1	standard polar	2025-10-24	1617.76
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_3	C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1	standard polar	2025-10-24	2084.65
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_4	C[C@H](O)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1	standard polar	2025-10-24	1679.93
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_5	C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O)=C2N1[Si](C)(C)C	standard polar	2025-10-24	1999.05
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_6	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O)=C2N1	standard polar	2025-10-24	2043.78
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_7	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1	standard polar	2025-10-24	1749.89
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_8	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1	standard polar	2025-10-24	2621.73
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_9	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CNC2=NC=NC(O)=C2N1[Si](C)(C)C	standard polar	2025-10-24	1698.2
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_10	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1	standard polar	2025-10-24	1429.63
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_11	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1	standard polar	2025-10-24	2219.35
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_12	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O)=C2N1[Si](C)(C)C	standard polar	2025-10-24	2769.13
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_13	C[C@H](O)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1	standard polar	2025-10-24	1570.57
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_14	C[C@H](O)C(O)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard polar	2025-10-24	1841.24
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_15	C[C@H](O)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1[Si](C)(C)C	standard polar	2025-10-24	975.505
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_16	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1	standard polar	2025-10-24	2866.84
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_17	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1	standard polar	2025-10-24	1803.49
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_18	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O)=C2N1[Si](C)(C)C	standard polar	2025-10-24	1447.11
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_19	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1	standard polar	2025-10-24	1995.73
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_20	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard polar	2025-10-24	1770.36
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_21	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1[Si](C)(C)C	standard polar	2025-10-24	2061.36
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_22	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1	standard polar	2025-10-24	1989.36
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_23	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard polar	2025-10-24	2151.77
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_24	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1[Si](C)(C)C	standard polar	2025-10-24	2875.13
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_25	C[C@H](O)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard polar	2025-10-24	3002.81
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_26	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1	standard polar	2025-10-24	2701.4
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_27	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CNC2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard polar	2025-10-24	1470.82
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_28	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O)=C2N1[Si](C)(C)C	standard polar	2025-10-24	2509.5
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_29	C[C@H](O[Si](C)(C)C)C(O)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard polar	2025-10-24	1876.86
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_30	C[C@H](O)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard polar	2025-10-24	2148.53
Gas Chromatography	(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin_TMS_31	C[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@H]1CN([Si](C)(C)C)C2=NC=NC(O[Si](C)(C)C)=C2N1[Si](C)(C)C	standard polar	2025-10-24	2044.87

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	3	Human feces; Human saliva	Unknown
Bacteria/Eubacteria	Proteobacteria	161	Human ; Human feces; River trout ; Turkey ; Sheep ; Pig ; American dog tick
Bacteria/Eubacteria	Acidobacteria	3
Bacteria/Eubacteria	Firmicutes	1
Bacteria/Eubacteria	Aquificae	1
Bacteria/Eubacteria	Chloroflexi	7
Bacteria/Eubacteria	Chlorobi	5
Bacteria/Eubacteria	Cyanobacteria	22	Human
Bacteria/Eubacteria	Bacteroidetes	2
Archaea/Archaea	Euryarchaeota	5
Archaea/Archaea	Crenarchaeota	6
Bacteria/Eubacteria	Actinobacteria	21	Human ; Cattle
Bacteria/Eubacteria	Verrucomicrobia	1
Archaea	Crenarchaeota	1
Bacteria	nah	1
Bacteria	Proteobacteria	1	Human ; Human feces; River trout ; Turkey ; Sheep ; Pig ; American dog tick

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

6398967

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

CMMC Knowledgebase

Not Available

General References

Bansal P, Morgat A, Axelsen KB, Muthukrishnan V, Coudert E, Aimo L, Hyka-Nouspikel N, Gasteiger E, Kerhornou A, Neto TB, Pozzato M, Blatter MC, Ignatchenko A, Redaschi N, Bridge A: Rhea, the reaction knowledgebase in 2022. Nucleic Acids Res. 2022 Jan 7;50(D1):D693-D700. doi: 10.1093/nar/gkab1016. [PubMed:34755880 ]

Showing metabocard for (6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin (MMDBc0033199)

MOL for #<Metabolite:0x00007f9af1b26568>

3D MOL for #<Metabolite:0x00007f9af1b26568>

3D SDF for #<Metabolite:0x00007f9af1b26568>

3D-SDF for #<Metabolite:0x00007f9af1b26568>

PDB for #<Metabolite:0x00007f9af1b26568>

3D PDB for #<Metabolite:0x00007f9af1b26568>

SMILES for #<Metabolite:0x00007f9af1b26568>

INCHI for #<Metabolite:0x00007f9af1b26568>

Structure for #<Metabolite:0x00007f9af1b26568>

3D Structure for #<Metabolite:0x00007f9af1b26568>