MiMeDB: Showing metabocard for lanosteryl oleate (MMDBc0033025)

Microbial

Record Information

Version

2.0

Status

Detected and Quantified

Creation Date

2021-11-19 04:31:36 UTC

Update Date

2025-10-07 16:07:53 UTC

Metabolite ID

MMDBc0033025

Metabolite Identification

Common Name

lanosteryl oleate

Description

Lanosteryl oleate is a lipid metabolite belonging to the class of sterol esters. It is derived from the transesterification of lanosterol, a tetracyclic triterpene, with oleic acid, resulting in a compound that features a long hydrocarbon chain attached to the sterol backbone. The chemical structure of lanosteryl oleate consists of a lanosterol moiety linked to an oleate group via an ester bond, which influences its solubility and biological interactions. Lanosteryl oleate is involved in various biochemical pathways, particularly in lipid metabolism and cellular signaling processes. Its formation occurs in the context of enzymatic reactions where lanosterol serves as a precursor, indicating its role in the biosynthesis of complex lipids. Notably, studies have shown that cholesterol can be transesterified with ethyl dihydrocinnamate to produce cholesteryl dihydrocinnamate, while the corresponding reaction with lanosterol yields lanosteryl oleate in a lower yield (14%) (PMID:11714305 ). This highlights the chemical versatility of lanosterol and its potential applications in the development of lipid-based formulations.

Structure

MOL SDF PDB SMILES InChI


  Mrv0541 02241222242D          

 52 55  0  0  1  0            999 V2000
   -2.1733   -0.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -0.8118    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -1.6509    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7587   -2.0631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -0.8118    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7587    0.3930    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279    0.8130    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6718    0.3930    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6718   -0.4151    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4565   -0.6719    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9228   -0.0188    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4565    0.6494    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6718    1.2404    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -0.0033    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1796    1.0539    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6291   -2.0818    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7587   -0.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7421    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279   -0.8118    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279   -1.6509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8855    1.4968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5999    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3144    1.4968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3144    0.6718    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1710    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4565    1.4968    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.0289    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -1.6509    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4736   -2.4759    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9598   -2.8600    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1733   -2.0631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3868   -2.8600    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6718   -1.2401    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6291   -2.9068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8011   -7.8740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0893   -8.2908    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9172   -3.3237    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3461   -3.3151    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9221   -4.1487    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2102   -4.5656    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2151   -5.3904    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5032   -5.8072    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5082   -6.6323    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7961   -7.0491    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6278   -7.8826    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3397   -8.2995    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0566   -7.8913    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7686   -8.3081    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4856   -7.8999    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1975   -8.3166    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9145   -7.9085    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6265   -8.3253    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  9  8  1  0  0  0  0
 12  8  1  0  0  0  0
  7  8  1  0  0  0  0
  8 13  1  1  0  0  0
 19  9  1  0  0  0  0
 10  9  1  0  0  0  0
  9 33  1  6  0  0  0
 17  6  1  0  0  0  0
 17  5  1  0  0  0  0
 19 17  2  0  0  0  0
 20 19  1  0  0  0  0
 28  5  1  0  0  0  0
  5 14  1  1  0  0  0
  1  5  1  0  0  0  0
 11 12  1  0  0  0  0
 26 12  1  0  0  0  0
 12 15  1  6  0  0  0
  6  7  1  0  0  0  0
 11 10  1  0  0  0  0
  4 20  1  0  0  0  0
 31 28  1  0  0  0  0
  4 28  1  0  0  0  0
  2  1  1  0  0  0  0
  3 31  1  0  0  0  0
  3  2  1  0  0  0  0
  3 16  1  1  0  0  0
 26 18  1  6  0  0  0
 25 21  1  0  0  0  0
 22 21  1  0  0  0  0
 23 22  2  0  0  0  0
 24 23  1  0  0  0  0
 27 23  1  0  0  0  0
 25 26  1  0  0  0  0
 28 29  1  6  0  0  0
 31 30  1  0  0  0  0
 31 32  1  0  0  0  0
 16 34  1  0  0  0  0
 34 37  1  0  0  0  0
 34 38  2  0  0  0  0
 44 35  1  0  0  0  0
 35 36  2  0  0  0  0
 45 36  1  0  0  0  0
 37 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
 43 44  1  0  0  0  0
 46 45  1  0  0  0  0
 47 46  1  0  0  0  0
 48 47  1  0  0  0  0
 49 48  1  0  0  0  0
 50 49  1  0  0  0  0
 51 50  1  0  0  0  0
 52 51  1  0  0  0  0
M  END


  Mrv0541 02241222242D          

 52 55  0  0  1  0            999 V2000
   -2.1733   -0.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -0.8118    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8959   -1.6509    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7587   -2.0631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -0.8118    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -0.7587    0.3930    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279    0.8130    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6718    0.3930    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.6718   -0.4151    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    1.4565   -0.6719    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9228   -0.0188    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4565    0.6494    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6718    1.2404    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -0.0033    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1796    1.0539    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6291   -2.0818    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7587   -0.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7421    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279   -0.8118    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0279   -1.6509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8855    1.4968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5999    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3144    1.4968    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3144    0.6718    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1710    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4565    1.4968    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    5.0289    1.9093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4736   -1.6509    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.4736   -2.4759    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9598   -2.8600    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1733   -2.0631    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3868   -2.8600    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6718   -1.2401    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6291   -2.9068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8011   -7.8740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0893   -8.2908    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9172   -3.3237    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3461   -3.3151    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9221   -4.1487    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2102   -4.5656    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2151   -5.3904    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5032   -5.8072    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5082   -6.6323    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7961   -7.0491    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6278   -7.8826    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3397   -8.2995    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0566   -7.8913    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7686   -8.3081    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4856   -7.8999    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1975   -8.3166    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9145   -7.9085    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6265   -8.3253    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  9  8  1  0  0  0  0
 12  8  1  0  0  0  0
  7  8  1  0  0  0  0
  8 13  1  1  0  0  0
 19  9  1  0  0  0  0
 10  9  1  0  0  0  0
  9 33  1  6  0  0  0
 17  6  1  0  0  0  0
 17  5  1  0  0  0  0
 19 17  2  0  0  0  0
 20 19  1  0  0  0  0
 28  5  1  0  0  0  0
  5 14  1  1  0  0  0
  1  5  1  0  0  0  0
 11 12  1  0  0  0  0
 26 12  1  0  0  0  0
 12 15  1  6  0  0  0
  6  7  1  0  0  0  0
 11 10  1  0  0  0  0
  4 20  1  0  0  0  0
 31 28  1  0  0  0  0
  4 28  1  0  0  0  0
  2  1  1  0  0  0  0
  3 31  1  0  0  0  0
  3  2  1  0  0  0  0
  3 16  1  1  0  0  0
 26 18  1  6  0  0  0
 25 21  1  0  0  0  0
 22 21  1  0  0  0  0
 23 22  2  0  0  0  0
 24 23  1  0  0  0  0
 27 23  1  0  0  0  0
 25 26  1  0  0  0  0
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 31 30  1  0  0  0  0
 31 32  1  0  0  0  0
 16 34  1  0  0  0  0
 34 37  1  0  0  0  0
 34 38  2  0  0  0  0
 44 35  1  0  0  0  0
 35 36  2  0  0  0  0
 45 36  1  0  0  0  0
 37 39  1  0  0  0  0
 39 40  1  0  0  0  0
 40 41  1  0  0  0  0
 41 42  1  0  0  0  0
 42 43  1  0  0  0  0
 43 44  1  0  0  0  0
 46 45  1  0  0  0  0
 47 46  1  0  0  0  0
 48 47  1  0  0  0  0
 49 48  1  0  0  0  0
 50 49  1  0  0  0  0
 51 50  1  0  0  0  0
 52 51  1  0  0  0  0
M  END
> <DATABASE_ID>
MMDBc0033025

> <DATABASE_NAME>
MIME

> <SMILES>
CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H]1CC[C@]2(C)C3=C(CC[C@@]2([H])C1(C)C)[C@]1(C)CC[C@]([H])([C@H](C)CCC=C(C)C)[C@@]1(C)CC3

> <INCHI_IDENTIFIER>
InChI=1S/C48H82O2/c1-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-28-44(49)50-43-33-34-46(7)40-32-36-47(8)39(38(4)27-25-26-37(2)3)31-35-48(47,9)41(40)29-30-42(46)45(43,5)6/h17-18,26,38-39,42-43H,10-16,19-25,27-36H2,1-9H3/b18-17-/t38-,39-,42+,43+,46-,47-,48+/m1/s1

> <INCHI_KEY>
DKYFEOWQCCNWLB-GYZZQDEESA-N

> <FORMULA>
C48H82O2

> <MOLECULAR_WEIGHT>
691.1635

> <EXACT_MASS>
690.631481868

> <JCHEM_ACCEPTOR_COUNT>
1

> <JCHEM_AVERAGE_POLARIZABILITY>
92.28944530549569

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S,5S,7R,11R,14R,15R)-2,6,6,11,15-pentamethyl-14-[(2R)-6-methylhept-5-en-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(10)-en-5-yl (9Z)-octadec-9-enoate

> <ALOGPS_LOGP>
11.04

> <JCHEM_LOGP>
15.154942096666668

> <ALOGPS_LOGS>
-7.57

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-7.042705895821048

> <JCHEM_POLAR_SURFACE_AREA>
26.3

> <JCHEM_REFRACTIVITY>
218.4547

> <JCHEM_ROTATABLE_BOND_COUNT>
21

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.87e-05 g/l

> <JCHEM_TRADITIONAL_IUPAC>
lanosteryl oleate

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 24-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   24-FEB-12         0                                  
HETATM    1  C   UNK     0      -4.057  -0.775   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      -5.406  -1.515   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      -5.406  -3.082   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -1.416  -3.851   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -2.751  -1.515   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -1.416   0.734   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -0.052   1.518   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       1.254   0.734   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0       1.254  -0.775   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0       2.719  -1.254   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0       3.589  -0.035   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0       2.719   1.212   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       1.254   2.315   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      -2.751  -0.006   0.000  0.00  0.00           C+0
HETATM   15  H   UNK     0       4.069   1.967   0.000  0.00  0.00           H+0
HETATM   16  O   UNK     0      -6.774  -3.886   0.000  0.00  0.00           O+0
HETATM   17  C   UNK     0      -1.416  -0.775   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0       1.385   3.564   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      -0.052  -1.515   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      -0.052  -3.082   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0       5.386   2.794   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0       6.720   3.564   0.000  0.00  0.00           C+0
HETATM   23  C   UNK     0       8.054   2.794   0.000  0.00  0.00           C+0
HETATM   24  C   UNK     0       8.054   1.254   0.000  0.00  0.00           C+0
HETATM   25  C   UNK     0       4.053   3.564   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0       2.719   2.794   0.000  0.00  0.00           C+0
HETATM   27  C   UNK     0       9.387   3.564   0.000  0.00  0.00           C+0
HETATM   28  C   UNK     0      -2.751  -3.082   0.000  0.00  0.00           C+0
HETATM   29  H   UNK     0      -2.751  -4.622   0.000  0.00  0.00           H+0
HETATM   30  C   UNK     0      -3.658  -5.339   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      -4.057  -3.851   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      -4.455  -5.339   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0       1.254  -2.315   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      -6.774  -5.426   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      -1.495 -14.698   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      -0.167 -15.476   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      -5.445  -6.204   0.000  0.00  0.00           C+0
HETATM   38  O   UNK     0      -8.113  -6.188   0.000  0.00  0.00           O+0
HETATM   39  C   UNK     0      -5.455  -7.744   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0      -4.126  -8.522   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0      -4.135 -10.062   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0      -2.806 -10.840   0.000  0.00  0.00           C+0
HETATM   43  C   UNK     0      -2.815 -12.380   0.000  0.00  0.00           C+0
HETATM   44  C   UNK     0      -1.486 -13.158   0.000  0.00  0.00           C+0
HETATM   45  C   UNK     0       1.172 -14.714   0.000  0.00  0.00           C+0
HETATM   46  C   UNK     0       2.501 -15.492   0.000  0.00  0.00           C+0
HETATM   47  C   UNK     0       3.839 -14.730   0.000  0.00  0.00           C+0
HETATM   48  C   UNK     0       5.168 -15.508   0.000  0.00  0.00           C+0
HETATM   49  C   UNK     0       6.506 -14.746   0.000  0.00  0.00           C+0
HETATM   50  C   UNK     0       7.835 -15.524   0.000  0.00  0.00           C+0
HETATM   51  C   UNK     0       9.174 -14.763   0.000  0.00  0.00           C+0
HETATM   52  C   UNK     0      10.503 -15.541   0.000  0.00  0.00           C+0
CONECT    1    5    2                                                       
CONECT    2    1    3                                                       
CONECT    3   31    2   16                                                  
CONECT    4   20   28                                                       
CONECT    5   17   28   14    1                                             
CONECT    6   17    7                                                       
CONECT    7    8    6                                                       
CONECT    8    9   12    7   13                                             
CONECT    9    8   19   10   33                                             
CONECT   10    9   11                                                       
CONECT   11   12   10                                                       
CONECT   12    8   11   26   15                                             
CONECT   13    8                                                            
CONECT   14    5                                                            
CONECT   15   12                                                            
CONECT   16    3   34                                                       
CONECT   17    6    5   19                                                  
CONECT   18   26                                                            
CONECT   19    9   17   20                                                  
CONECT   20   19    4                                                       
CONECT   21   25   22                                                       
CONECT   22   21   23                                                       
CONECT   23   22   24   27                                                  
CONECT   24   23                                                            
CONECT   25   21   26                                                       
CONECT   26   12   18   25                                                  
CONECT   27   23                                                            
CONECT   28    5   31    4   29                                             
CONECT   29   28                                                            
CONECT   30   31                                                            
CONECT   31   28    3   30   32                                             
CONECT   32   31                                                            
CONECT   33    9                                                            
CONECT   34   16   37   38                                                  
CONECT   35   44   36                                                       
CONECT   36   35   45                                                       
CONECT   37   34   39                                                       
CONECT   38   34                                                            
CONECT   39   37   40                                                       
CONECT   40   39   41                                                       
CONECT   41   40   42                                                       
CONECT   42   41   43                                                       
CONECT   43   42   44                                                       
CONECT   44   35   43                                                       
CONECT   45   36   46                                                       
CONECT   46   45   47                                                       
CONECT   47   46   48                                                       
CONECT   48   47   49                                                       
CONECT   49   48   50                                                       
CONECT   50   49   51                                                       
CONECT   51   50   52                                                       
CONECT   52   51                                                            
MASTER        0    0    0    0    0    0    0    0   52    0  110    0
END

Synonyms

Value	Source
Lanosteryl oleic acid	Generator
Lanosta-8,24-dien-3β-yl (9Z)-octadec-9-enoate	MetaCyc
Lanosta-8,24-dien-3β-yl (9Z)-octadec-9-enoic acid	Generator

Molecular Formula

C₄₈H₈₂O₂

Average Mass

691.1635

Monoisotopic Mass

690.631481868

IUPAC Name

(2S,5S,7R,11R,14R,15R)-2,6,6,11,15-pentamethyl-14-[(2R)-6-methylhept-5-en-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(10)-en-5-yl (9Z)-octadec-9-enoate

Traditional Name

lanosteryl oleate

CAS Registry Number

Not Available

SMILES

CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H]1CC[C@]2(C)C3=C(CC[C@@]2([H])C1(C)C)[C@]1(C)CC[C@]([H])([C@H](C)CCC=C(C)C)[C@@]1(C)CC3

InChI Identifier

InChI=1S/C48H82O2/c1-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-28-44(49)50-43-33-34-46(7)40-32-36-47(8)39(38(4)27-25-26-37(2)3)31-35-48(47,9)41(40)29-30-42(46)45(43,5)6/h17-18,26,38-39,42-43H,10-16,19-25,27-36H2,1-9H3/b18-17-/t38-,39-,42+,43+,46-,47-,48+/m1/s1

InChI Key

DKYFEOWQCCNWLB-GYZZQDEESA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Prenol lipids

Sub Class

Triterpenoids

Direct Parent

Triterpenoids

Alternative Parents

Substituents

Triterpenoid
Steroid ester
14-alpha-methylsteroid
Steroid
Carboxylic acid ester
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic homopolycyclic compound

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

lanosteryl ester (CHEBI:52382 )
Steryl esters (LMST01020032 )

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Property	Value	Source
Water Solubility	1.9e-05 g/L	ALOGPS
logP	11.04	ALOGPS
logP	15.15	ChemAxon
logS	-7.6	ALOGPS
pKa (Strongest Basic)	-7	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	1	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	26.3 Å²	ChemAxon
Rotatable Bond Count	21	ChemAxon
Refractivity	218.45 m³·mol⁻¹	ChemAxon
Polarizability	92.29 Å³	ChemAxon
Number of Rings	4	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-00kf-0140409000-1088da55ff41d3a84b64	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-06fr-3393714000-51c71e430575dd62bec7	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-014j-4259124000-64be68215e431f63c577	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-000i-0020509000-900c74ea58c66d174614	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-004r-0040903000-c2972d753b7e9e133ddc	2016-09-12	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-0a6u-3022900000-73df0c3ceab378e5d1e3	2016-09-12	View Spectrum
MS	Mass Spectrum (Electron Ionization)	Not Available	2022-08-06	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)		2022-08-20	View Spectrum

Chromatographic Retention Times and Retention Indices

Retention Times

Chromatography Type	Technique	Column	Deposition Date	Retention Time (s)
Liquid Chromatography	HILIC	Waters Acquity UPLC-BEH Amide column (void)	2025-10-24	190.8
Liquid Chromatography	HILIC	Accucore 150 Amide HILIC (void)	2025-10-24	69.9
Liquid Chromatography	Reversed-phase	Hypersil Gold 1.9 µm C18 (eluted)	2025-10-24	1335.7
Liquid Chromatography	Reversed-phase	Agilent Zorbax Eclipse Plus C18 (2.1 mm x 150 mm, 3.5 um) (eluted)	2025-10-24	1898.2
Liquid Chromatography	Reversed-phase	XBridge C18 3.5u 2.1x50 mm (eluted)	2025-10-24	2264.1
Liquid Chromatography	Reversed-phase	Ascentis Express C18 (eluted)	2025-10-24	1490.1
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	5942.6
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (void)	2025-10-24	137.7
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC (eluted)	2025-10-24	529.4
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	2013.2
Liquid Chromatography	HILIC	Merck SeQuant ZIC-HILIC (eluted)	2025-10-24	1343.4
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC HSS T3 C18 (eluted)	2025-10-24	679.2
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	573.1
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (eluted)	2025-10-24	11.4
Liquid Chromatography	HILIC	Merck SeQuant ZIC-pHILIC column (void)	2025-10-24	759.3
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	1207.9
Liquid Chromatography	Reversed-phase	Waters ACQUITY UPLC BEH C18 (eluted)	2025-10-24	1063.5
Liquid Chromatography	Reversed-phase	Kinetex Core-Shell C18 2.6 um, 3.0 x 100 mm, Phenomenex (eluted)	2025-10-24	3650.8
Liquid Chromatography	Reversed-phase	Waters Atlantis T3 (2.1 x 150 mm, 5 um) (eluted)	2025-10-24	4391.9

Retention Indices

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	1	Human feces; Human saliva	Unknown

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

25271609

PDB ID

Not Available

ChEBI ID

52382

Food Biomarker Ontology

Not Available

CMMC Knowledgebase

Not Available

General References

Zweytick D, Leitner E, Kohlwein SD, Yu C, Rothblatt J, Daum G: Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae. Eur J Biochem. 2000 Feb;267(4):1075-82. doi: 10.1046/j.1432-1327.2000.01103.x. [PubMed:10672016 ]
Herrgard MJ, Swainston N, Dobson P, Dunn WB, Arga KY, Arvas M, Bluthgen N, Borger S, Costenoble R, Heinemann M, Hucka M, Le Novere N, Li P, Liebermeister W, Mo ML, Oliveira AP, Petranovic D, Pettifer S, Simeonidis E, Smallbone K, Spasic I, Weichart D, Brent R, Broomhead DS, Westerhoff HV, Kirdar B, Penttila M, Klipp E, Palsson BO, Sauer U, Oliver SG, Mendes P, Nielsen J, Kell DB: A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nat Biotechnol. 2008 Oct;26(10):1155-60. doi: 10.1038/nbt1492. [PubMed:18846089 ]

Showing metabocard for lanosteryl oleate (MMDBc0033025)

MOL for #<Metabolite:0x00005643231064b0>

3D MOL for #<Metabolite:0x00005643231064b0>

3D SDF for #<Metabolite:0x00005643231064b0>

3D-SDF for #<Metabolite:0x00005643231064b0>

PDB for #<Metabolite:0x00005643231064b0>

3D PDB for #<Metabolite:0x00005643231064b0>

SMILES for #<Metabolite:0x00005643231064b0>

INCHI for #<Metabolite:0x00005643231064b0>

Structure for #<Metabolite:0x00005643231064b0>

3D Structure for #<Metabolite:0x00005643231064b0>