MiMeDB: Showing metabocard for FAD (MMDBc0000567)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2020-12-10 18:40:42 UTC

Update Date

2024-10-10 00:59:20 UTC

Metabolite ID

MMDBc0000567

Metabolite Identification

Common Name

FAD

Description

Flavin adenine dinucleotide (FAD) is a redox-active coenzyme associated with various proteins, which is involved with several enzymatic reactions in metabolism. FAD, also known as adeflavin or flamitajin b, belongs to the class of organic compounds known as flavin nucleotides. These are nucleotides containing a flavin moiety. Flavin is a compound that contains the tricyclic isoalloxazine ring system, which bears 2 oxo groups at the 2- and 4-positions. FAD is a drug which is used to treat eye diseases caused by vitamin b2 deficiency, such as keratitis and blepharitis. FAD exists in all living species, ranging from bacteria to humans. In humans, FAD is involved in the metabolic disorder called the medium chain acyl-coa dehydrogenase deficiency (mcad) pathway. Outside of the human body, FAD has been detected, but not quantified in several different foods, such as other bread, passion fruits, asparagus, kelps, and green bell peppers. It is a flavoprotein in which the substituent at position 10 of the flavin nucleus is a 5'-adenosyldiphosphoribityl group.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Molecular Formula

C₂₇H₃₃N₉O₁₅P₂

Average Mass

785.5497

Monoisotopic Mass

785.157134455

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C27H33N9O15P2/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43)/t14-,15+,16+,19-,20+,21+,26+/m0/s1

InChI Key

VWWQXMAJTJZDQX-UYBVJOGSSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Expected Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Cytoplasm
Endoplasmic reticulum
Mitochondria
Peroxisome

Biospecimen Locations

Blood
Erythrocyte
Feces
Liver
Placenta
Skeletal Muscle

Tissue Locations

Erythrocyte
Liver
Placenta
Skeletal Muscle

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species
MMDBp0191728	Dihydrolipoyl dehydrogenase, mitochondrial	Unknown	P09622	Homo sapiens
MMDBp0191775	Long-chain specific acyl-CoA dehydrogenase, mitochondrial	Unknown	P28330	Homo sapiens
MMDBp0191776	Short-chain specific acyl-CoA dehydrogenase, mitochondrial	Unknown	P16219	Homo sapiens
MMDBp0191777	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	Unknown	P11310	Homo sapiens
MMDBp0191788	NADH-ubiquinone oxidoreductase chain 1	Unknown	P03886	Homo sapiens
MMDBp0191789	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1	Enzyme	O75438	Homo sapiens
MMDBp0191790	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	Unknown	P22413	Homo sapiens
MMDBp0191791	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	Unknown	O75306	Homo sapiens
MMDBp0191792	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	Unknown	Q99643	Homo sapiens
MMDBp0191793	Peroxisomal sarcosine oxidase	Unknown	Q9P0Z9	Homo sapiens
MMDBp0191794	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	Unknown	Q6QHF9	Homo sapiens
MMDBp0191795	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	Enzyme	Q9UI09	Homo sapiens
MMDBp0191796	NADH-cytochrome b5 reductase 3	Unknown	P00387	Homo sapiens
MMDBp0191797	Aldehyde oxidase	Unknown	Q06278	Homo sapiens
MMDBp0191798	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	Enzyme	O15239	Homo sapiens
MMDBp0191799	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2	Enzyme	Q9NRX3	Homo sapiens
MMDBp0191800	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3	Enzyme	O95167	Homo sapiens
MMDBp0191801	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8	Enzyme	P51970	Homo sapiens
MMDBp0191802	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4	Enzyme	O00483	Homo sapiens
MMDBp0191803	NADH-ubiquinone oxidoreductase chain 4L	Unknown	P03901	Homo sapiens
MMDBp0191804	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	Enzyme	Q86Y39	Homo sapiens
MMDBp0191805	Thioredoxin reductase 1, cytoplasmic	Unknown	Q16881	Homo sapiens
MMDBp0191806	Lathosterol oxidase	Unknown	O75845	Homo sapiens
MMDBp0191808	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	Unknown	O43181	Homo sapiens
MMDBp0191809	Ribosyldihydronicotinamide dehydrogenase [quinone]	Unknown	P16083	Homo sapiens
MMDBp0191811	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	Unknown	O75489	Homo sapiens
MMDBp0191812	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5	Unknown	O43920	Homo sapiens
MMDBp0191813	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	Unknown	P19404	Homo sapiens
MMDBp0191814	Dimethylaniline monooxygenase [N-oxide-forming] 5	Unknown	P49326	Homo sapiens
MMDBp0191815	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	Unknown	O95299	Homo sapiens
MMDBp0191816	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	Enzyme	P56556	Homo sapiens
MMDBp0191817	Peroxisomal acyl-coenzyme A oxidase 1	Unknown	Q15067	Homo sapiens
MMDBp0191818	D-aspartate oxidase	Unknown	Q99489	Homo sapiens
MMDBp0191820	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4	Enzyme	O95168	Homo sapiens
MMDBp0191821	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	Unknown	P31040	Homo sapiens
MMDBp0191822	Heme oxygenase 2	Unknown	P30519	Homo sapiens
MMDBp0191823	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	Unknown	O00217	Homo sapiens
MMDBp0191824	Squalene monooxygenase	Unknown	Q14534	Homo sapiens
MMDBp0191825	NADH-ubiquinone oxidoreductase chain 2	Unknown	P03891	Homo sapiens
MMDBp0191826	Dimethylaniline monooxygenase [N-oxide-forming] 2	Unknown	Q99518	Homo sapiens
MMDBp0191828	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7	Enzyme	O95182	Homo sapiens
MMDBp0191829	Thioredoxin reductase 2, mitochondrial	Unknown	Q9NNW7	Homo sapiens
MMDBp0191830	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	Enzyme	O43678	Homo sapiens
MMDBp0191831	Methionine synthase	Unknown	Q99707	Homo sapiens
MMDBp0191832	Amine oxidase [flavin-containing] B	Unknown	P27338	Homo sapiens
MMDBp0191833	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	Unknown	P28331	Homo sapiens
MMDBp0191834	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial	Enzyme	O43674	Homo sapiens
MMDBp0191835	Peroxisomal acyl-coenzyme A oxidase 2	Unknown	Q99424	Homo sapiens
MMDBp0191836	Dimethylaniline monooxygenase [N-oxide-forming] 4	Unknown	P31512	Homo sapiens
MMDBp0191837	Isovaleryl-CoA dehydrogenase, mitochondrial	Unknown	P26440	Homo sapiens
MMDBp0191840	Amine oxidase [flavin-containing] A	Unknown	P21397	Homo sapiens
MMDBp0191841	NADH dehydrogenase [ubiquinone] 1 subunit C2	Enzyme	O95298	Homo sapiens
MMDBp0191842	Dimethylaniline monooxygenase [N-oxide-forming] 3	Unknown	P31513	Homo sapiens
MMDBp0191843	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	Enzyme	O43676	Homo sapiens
MMDBp0191844	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7	Enzyme	P17568	Homo sapiens
MMDBp0191845	Acyl carrier protein, mitochondrial	Enzyme	O14561	Homo sapiens
MMDBp0191846	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	Enzyme	Q16718	Homo sapiens
MMDBp0191847	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	Unknown	Q16134	Homo sapiens
MMDBp0191848	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial	Unknown	Q16795	Homo sapiens
MMDBp0191849	NADH-ubiquinone oxidoreductase chain 4	Unknown	P03905	Homo sapiens
MMDBp0191850	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial	Unknown	O14521	Homo sapiens
MMDBp0191851	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	Unknown	O75251	Homo sapiens
MMDBp0191852	Xanthine dehydrogenase/oxidase	Unknown	P47989	Homo sapiens
MMDBp0191854	NADPH--cytochrome P450 reductase	Unknown	P16435	Homo sapiens
MMDBp0191855	Dihydroorotate dehydrogenase (quinone), mitochondrial	Unknown	Q02127	Homo sapiens
MMDBp0191856	Dimethylaniline monooxygenase [N-oxide-forming] 1	Unknown	Q01740	Homo sapiens
MMDBp0191857	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	Unknown	P49821	Homo sapiens
MMDBp0191858	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	Enzyme	Q9Y6M9	Homo sapiens
MMDBp0191859	Methylenetetrahydrofolate reductase	Unknown	P42898	Homo sapiens
MMDBp0191860	NADH-ubiquinone oxidoreductase chain 6	Unknown	P03923	Homo sapiens
MMDBp0191861	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Enzyme	Q9P0J0	Homo sapiens
MMDBp0191862	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	Unknown	O75380	Homo sapiens
MMDBp0191863	Peroxisomal acyl-coenzyme A oxidase 3	Unknown	O15254	Homo sapiens
MMDBp0191864	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	Unknown	P21912	Homo sapiens
MMDBp0191865	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3	Unknown	O14638	Homo sapiens
MMDBp0191867	Glutathione reductase, mitochondrial	Unknown	P00390	Homo sapiens
MMDBp0191868	Glycerol-3-phosphate dehydrogenase, mitochondrial	Unknown	P43304	Homo sapiens
MMDBp0191869	Heme oxygenase 1	Unknown	P09601	Homo sapiens
MMDBp0191870	Retinal dehydrogenase 1	Unknown	P00352	Homo sapiens
MMDBp0191872	Choline dehydrogenase, mitochondrial	Unknown	Q8NE62	Homo sapiens
MMDBp0191873	Glutaryl-CoA dehydrogenase, mitochondrial	Unknown	Q92947	Homo sapiens
MMDBp0191874	Dimethylglycine dehydrogenase, mitochondrial	Unknown	Q9UI17	Homo sapiens
MMDBp0191875	NADPH:adrenodoxin oxidoreductase, mitochondrial	Unknown	P22570	Homo sapiens
MMDBp0191876	Retinal dehydrogenase 2	Unknown	O94788	Homo sapiens
MMDBp0191877	D-amino-acid oxidase	Unknown	P14920	Homo sapiens
MMDBp0192087	Methionine synthase reductase	Unknown	Q9UBK8	Homo sapiens
MMDBp0192153	tRNA-dihydrouridine synthase 2-like	Unknown	Q9NX74	Homo sapiens
MMDBp0192340	Flavin reductase (NADPH)	Unknown	P30043	Homo sapiens
MMDBp0192365	Dihydropyrimidine dehydrogenase [NADP(+)]	Unknown	Q12882	Homo sapiens
MMDBp0192413	Sarcosine dehydrogenase, mitochondrial	Unknown	Q9UL12	Homo sapiens
MMDBp0192544	Nitric oxide synthase, inducible	Unknown	P35228	Homo sapiens
MMDBp0192546	Nitric oxide synthase, brain	Unknown	P29475	Homo sapiens
MMDBp0192547	Nitric oxide synthase, endothelial	Unknown	P29474	Homo sapiens
MMDBp0192632	Protoporphyrinogen oxidase	Unknown	P50336	Homo sapiens
MMDBp0192712	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	Enzyme	Q9NX14	Homo sapiens
MMDBp0193097	Alkyldihydroxyacetonephosphate synthase, peroxisomal	Unknown	O00116	Homo sapiens
MMDBp0193161	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	Unknown	P45954	Homo sapiens
MMDBp0193201	NAD(P)H dehydrogenase [quinone] 1	Unknown	P15559	Homo sapiens
MMDBp0193244	Cytochrome b-245 heavy chain	Unknown	P04839	Homo sapiens
MMDBp0193274	Electron transfer flavoprotein subunit alpha, mitochondrial	Unknown	P13804	Homo sapiens
MMDBp0193320	Putative dimethylaniline monooxygenase [N-oxide-forming] 6	Unknown	O60774	Homo sapiens
MMDBp0193337	Delta(24)-sterol reductase	Unknown	Q15392	Homo sapiens
MMDBp0193367	Amyloid beta A4 protein	Unknown	P05067	Homo sapiens
MMDBp0193385	Electron transfer flavoprotein subunit beta	Unknown	P38117	Homo sapiens
MMDBp0193396	Proline dehydrogenase 1, mitochondrial	Unknown	O43272	Homo sapiens
MMDBp0191674	D-2-hydroxyglutarate dehydrogenase, mitochondrial	Enzyme	Q8N465	Saccharomyces cerevisiae
MMDBp0191676	L-2-hydroxyglutarate dehydrogenase, mitochondrial	Enzyme	Q9H9P8	Saccharomyces cerevisiae
MMDBp0193578	Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)	Enzyme	Q3LXA3	Homo sapiens
MMDBp0193603	Kynurenine 3-monooxygenase	Unknown	O15229	Homo sapiens
MMDBp0193618	Spermine oxidase	Unknown	Q9NWM0	Homo sapiens
MMDBp0193635	Apoptosis-inducing factor 1, mitochondrial	Unknown	O95831	Homo sapiens
MMDBp0193655	Cryptochrome-1	Unknown	Q16526	Homo sapiens
MMDBp0193809	Dual oxidase 2	Unknown	Q9NRD8	Homo sapiens
MMDBp0193922	Probable D-lactate dehydrogenase, mitochondrial	Unknown	Q86WU2	Homo sapiens
MMDBp0193998	Isobutyryl-CoA dehydrogenase, mitochondrial	Unknown	Q9UKU7	Homo sapiens
MMDBp0193999	Acyl-CoA dehydrogenase family member 9, mitochondrial	Unknown	Q9H845	Homo sapiens
MMDBp0194002	Probable proline dehydrogenase 2	Unknown	Q9UF12	Homo sapiens
MMDBp0194050	Dual oxidase 1	Unknown	Q9NRD9	Homo sapiens
MMDBp0194051	Thioredoxin reductase 3	Unknown	Q86VQ6	Homo sapiens
MMDBp0194062	NADH-cytochrome b5 reductase 1	Unknown	Q9UHQ9	Homo sapiens
MMDBp0194063	NADH-cytochrome b5 reductase 2	Unknown	Q6BCY4	Homo sapiens
MMDBp0194064	Cytochrome b5 reductase 4	Unknown	Q7L1T6	Homo sapiens
MMDBp0194065	NADH-cytochrome b5 reductase-like	Unknown	Q6IPT4	Homo sapiens
MMDBp0194153	Putative uncharacterized protein DKFZp686B0215	Enzyme	Q5HYI4	Homo sapiens
MMDBp0194187	FAD synthase	Unknown	Q8NFF5	Homo sapiens
MMDBp0194194	Ubiquinone biosynthesis monooxygenase COQ6	Unknown	Q9Y2Z9	Homo sapiens
MMDBp0194617	NADPH oxidase 5	Unknown	Q96PH1	Homo sapiens
MMDBp0194993	NADPH oxidase 3	Unknown	Q9HBY0	Homo sapiens
MMDBp0195029	Metalloreductase STEAP3	Unknown	Q658P3	Homo sapiens
MMDBp0195030	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Unknown	P49748	Homo sapiens
MMDBp0195031	Acyl-coenzyme A oxidase-like protein	Unknown	Q9NUZ1	Homo sapiens
MMDBp0195032	Apoptosis-inducing factor 2	Unknown	Q9BRQ8	Homo sapiens
MMDBp0195033	Apoptosis-inducing factor 3	Unknown	Q96NN9	Homo sapiens
MMDBp0195034	FAD-linked sulfhydryl oxidase ALR	Unknown	P55789	Homo sapiens
MMDBp0195035	Lysine-specific histone demethylase 1B	Unknown	Q8NB78	Homo sapiens
MMDBp0195036	Cryptochrome-2	Unknown	Q49AN0	Homo sapiens
MMDBp0195037	tRNA-dihydrouridine synthase 1-like	Unknown	Q6P1R4	Homo sapiens
MMDBp0195038	tRNA-dihydrouridine synthase 3-like	Unknown	Q96G46	Homo sapiens
MMDBp0195039	tRNA-dihydrouridine synthase 4-like	Unknown	O95620	Homo sapiens
MMDBp0195040	ERO1-like protein alpha	Unknown	Q96HE7	Homo sapiens
MMDBp0195041	ERO1-like protein beta	Unknown	Q86YB8	Homo sapiens
MMDBp0195042	FAD-dependent oxidoreductase domain-containing protein 1	Unknown	Q96CU9	Homo sapiens
MMDBp0195043	FAD-dependent oxidoreductase domain-containing protein 2	Unknown	Q8IWF2	Homo sapiens
MMDBp0195044	Lysine-specific histone demethylase 1A	Unknown	O60341	Homo sapiens
MMDBp0195045	Protein-methionine sulfoxide oxidase MICAL1	Unknown	Q8TDZ2	Homo sapiens
MMDBp0195046	Protein-methionine sulfoxide oxidase MICAL2	Unknown	O94851	Homo sapiens
MMDBp0195047	Protein-methionine sulfoxide oxidase MICAL3	Unknown	Q7RTP6	Homo sapiens
MMDBp0195048	Protein MTO1 homolog, mitochondrial	Unknown	Q9Y2Z2	Homo sapiens
MMDBp0195049	NADPH-dependent diflavin oxidoreductase 1	Unknown	Q9UHB4	Homo sapiens
MMDBp0195050	NADPH oxidase 1	Unknown	Q9Y5S8	Homo sapiens
MMDBp0195051	NADPH oxidase 4	Unknown	Q9NPH5	Homo sapiens
MMDBp0195052	L-amino-acid oxidase	Unknown	Q96RQ9	Homo sapiens
MMDBp0195053	Oxidoreductase NAD-binding domain-containing protein 1	Unknown	Q96HP4	Homo sapiens
MMDBp0195054	Prenylcysteine oxidase 1	Unknown	Q9UHG3	Homo sapiens
MMDBp0195055	Prenylcysteine oxidase-like	Unknown	Q8NBM8	Homo sapiens
MMDBp0195056	[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial	Unknown	Q9P2J9	Homo sapiens
MMDBp0195057	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1	Unknown	Q8WU10	Homo sapiens
MMDBp0195058	Sulfhydryl oxidase 1	Unknown	O00391	Homo sapiens
MMDBp0195059	Sulfhydryl oxidase 2	Unknown	Q6ZRP7	Homo sapiens
MMDBp0195060	Renalase	Unknown	Q5VYX0	Homo sapiens
MMDBp0195061	All-trans-retinol 13,14-reductase	Unknown	Q6NUM9	Homo sapiens
MMDBp0195062	Sulfide:quinone oxidoreductase, mitochondrial	Unknown	Q9Y6N5	Homo sapiens
MMDBp0195063	Metalloreductase STEAP1	Unknown	Q9UHE8	Homo sapiens
MMDBp0195064	Metalloreductase STEAP2	Unknown	Q8NFT2	Homo sapiens
MMDBp0195065	Metalloreductase STEAP4	Unknown	Q687X5	Homo sapiens
MMDBp0196143	NADH dehydrogenase (Ubiquinone) 1 beta subcomplex, 2, 8kDa	Enzyme	A4D1T5	Homo sapiens

Human Pathways

Pathways

Name	SMPDB/PathBank
Nitric Oxide Signaling Pathway
Ion Channels and Their Functional Role in Vascular Endothelium
NAD+ Signalling Pathway (Cancer)
NAD+ Signalling and Aging
Succinate Signalling During Inflammation

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Data Source	Reference
MMDBr0000193	2-Methylbutyryl-CoA	Tiglyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	11013134
MMDBr0000194	Butyryl-CoA	Crotonoyl-CoA	acyl-CoA dehydrogenase family, member 10	VMH; KEGG	2565344
MMDBr0000195	Isovaleryl-CoA	3-Methylcrotonyl-CoA	isovaleryl-CoA dehydrogenase	VMH; KEGG	9214289
MMDBr0000196	Isobutyryl-CoA	Methacrylyl-CoA	acyl-CoA dehydrogenase family, member 8	VMH	11013134
MMDBr0000201	3a,7a-Dihydroxy-5b-cholest-24-enoyl-CoA	3a,7a,12a-Trihydroxy-5b-cholestanoyl-CoA	acyl-CoA oxidase 2, branched chain	VMH	11181649
MMDBr0000472	Choline	Betaine aldehyde	choline dehydrogenase	VMH	15321791
MMDBr0000667	zymosterol intermediate 2	5a-Cholest-8-en-3b-ol	24-dehydrocholesterol reductase	VMH	17984220 19520779 19520780
MMDBr0000668	5a-Cholesta-7,24-dien-3b-ol	Lathosterol	cytochrome P450, family 7, subfamily A, polypeptide 1	VMH	17984220 19520779 19520780
MMDBr0000669	Desmosterol	Cholesterol	24-dehydrocholesterol reductase	VMH	17984220 19520779 19520780
MMDBr0000672	Dihydroceramide	Ceramide (d18:1/18:0)	delta(4)-desaturase, sphingolipid 1	VMH	9188692
MMDBr0000715	Dimethylglycine	Formaldehyde	dimethylglycine dehydrogenase	VMH	10767172 1123190
MMDBr0001132	FAD	Flavin mononucleotide	ectonucleotide pyrophosphatase/phosphodiesterase 1	VMH; KEGG	1315502
MMDBr0001148	Tetradecanoyl-CoA	Acetyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	2565344
MMDBr0001149	Pentadecanoyl Coenzyme A	Propionyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	2565344
MMDBr0001150	Palmityl-CoA	Acetyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	2565344 3035565
MMDBr0001151	Palmityl-CoA	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001153	(2E)-Hexadecenoyl-CoA	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001154	Palmitoleyl-CoA	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001155	Heptadecanoyl Coenzyme A	Propionyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	2565344
MMDBr0001156	Stearoyl-CoA	Palmityl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	2565344 3035565
MMDBr0001158	Trans-Octadec-2-enoyl-CoA	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001159	11-Octadecenoyl Coenzyme A	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001160	oleoyl-CoA	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001161	Linoleoyl-CoA	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001162	Alpha-Linolenoyl-CoA	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001165	Stearidonoyl CoA	Octanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001167	Eicosanoyl-CoA	Stearoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001169	8Z,11Z,14Z-eicosatrienoyl-CoA	Gamma-linolenoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001170	Arachidonyl-CoA	Acetyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	2565344 3035565
MMDBr0001171	Eicosatetranoyl coenzyme A	Stearidonoyl CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001174	Adrenyl coenzyme A	Arachidonyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	30371894
MMDBr0001180	Cervonyl Coenzyme A	Acetyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	2565344 3035565
MMDBr0001190	Octanoyl-CoA	Acetyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	2565344 3035565
MMDBr0001255	Glycerol 3-phosphate	Dihydroxyacetone phosphate	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	VMH	11385633 8549872
MMDBr0001344	Glutaryl-CoA	Crotonoyl-CoA	glutaryl-CoA dehydrogenase	VMH; KEGG	30371894
MMDBr0001974	Propionyl-CoA	Acrylyl-CoA	acyl-CoA dehydrogenase family, member 10	VMH	12359132 12359260 15560374 2565344 3035565 7698750 8276399
MMDBr0001999	L-Proline	L-D-1-Pyrroline-5-carboxylic acid	proline dehydrogenase (oxidase) 1	VMH; KEGG	30371894
MMDBr0002094	Sarcosine	Glycine	sarcosine dehydrogenase	VMH	10444331
MMDBr0002184	Succinic acid	Fumaric acid	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	VMH; KEGG	30371894
MMDBr0002975	oleoyl-CoA	Trans,Cis-Octadeca-2,9-Dienoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	30371894
MMDBr0003988	Linoleoyl-CoA	Trans,Cis,Cis-2,9,12-Octadecatrienoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	10407780 11356167 8973539
MMDBr0003989	Linoleoyl-CoA	Trans,Cis,Cis-2,9,12-Octadecatrienoyl Coenzyme A	acyl-CoA oxidase 1, palmitoyl	VMH	10407780 11356167 8973539
MMDBr0003990	Cis,Cis-Palmito-7,10-Dienoyl Coenzyme A	Trans,Cis,Cis-2,7,10-Hexadecatrienoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	10407780 11356167 8973539
MMDBr0003991	Cis,Cis-Palmito-7,10-Dienoyl Coenzyme A	Trans,Cis,Cis-2,7,10-Hexadecatrienoyl Coenzyme A	acyl-CoA oxidase 1, palmitoyl	VMH	10407780 11356167 8973539
MMDBr0003992	4-Decenoyl Coenzyme A	trans-Delta2, cis-delta4-decadienoyl-CoA	acyl-CoA oxidase 1, palmitoyl	VMH	10407780 11356167 8973539
MMDBr0004400	Palmitoleyl-CoA	Trans,Cis-Hexadeca-2,9-Dienoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	1047780 11135616 8973539
MMDBr0004401	Palmitoleyl-CoA	Trans,Cis-Hexadeca-2,9-Dienoyl Coenzyme A	acyl-CoA oxidase 1, palmitoyl	VMH	1047780 11135616 8973539
MMDBr0004402	Cis-Myrist-7-Enoyl Coenzyme A	Trans,Cis-Myristo-2,7-Dienoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	1047780 11135616 8973539
MMDBr0004403	Cis-Myrist-7-Enoyl Coenzyme A	Trans,Cis-Myristo-2,7-Dienoyl Coenzyme A	acyl-CoA oxidase 1, palmitoyl	VMH	1047780 11135616 8973539
MMDBr0004600	4(R),8-Dimethyl-Nonanoyl Coenzyme A	4(R),8-Dimethyl-Trans-2-Nonenoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	10407780 9469587 9819701
MMDBr0004601	2(S),6-Dimethyl-Heptanoyl Coenzyme A	2,6-Dimethyl-Trans-2-Heptenoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	10407780 9469587 9819701
MMDBr0004602	4-Methyl-Pentanoyl Coenzyme A	4-Methyl-Trans-2-Pentenoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	10407780 9469587 9819701
MMDBr0004686	Arachidonic acid	5,6-Epoxy-8,11,14-eicosatrienoic acid	Not Available	VMH	8651708
MMDBr0004687	Arachidonic acid	5,6-Epoxy-8,11,14-eicosatrienoic acid	cytochrome P450, family 19, subfamily A, polypeptide 1	VMH	8651708
MMDBr0004688	Arachidonic acid	11,12-Epoxyeicosatrienoic acid	Not Available	VMH	8651708
MMDBr0004689	Arachidonic acid	11,12-Epoxyeicosatrienoic acid	cytochrome P450, family 19, subfamily A, polypeptide 1	VMH	8651708
MMDBr0004690	Arachidonic acid	8,9-Epoxyeicosatrienoic acid	Not Available	VMH	8651708
MMDBr0004691	Arachidonic acid	8,9-Epoxyeicosatrienoic acid	cytochrome P450, family 19, subfamily A, polypeptide 1	VMH	8651708
MMDBr0004692	Arachidonic acid	14,15-Epoxy-5,8,11-eicosatrienoic acid	Not Available	VMH	8651708
MMDBr0004693	Arachidonic acid	14,15-Epoxy-5,8,11-eicosatrienoic acid	cytochrome P450, family 19, subfamily A, polypeptide 1	VMH	8651708
MMDBr0005175	4-Decenoyl Coenzyme A	trans-Delta2, cis-delta4-decadienoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	15337167
MMDBr0005183	4,7-Decadienoyl Coenzyme A	2,4,7-Decatrienoyl Coenzyme A	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	15337167
MMDBr0005191	Decanoyl-CoA (N-C10:0CoA)	(S)-Hydroxydecanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	1730577 1912723 7318031
MMDBr0005192	Decanoyl-CoA (N-C10:0CoA)	Octanoyl-CoA	acetyl-CoA acyltransferase 2	VMH	20195903 20490924 17143551
MMDBr0005196	Undecanoyl Coenzyme A	Nonanoyl Coenzyme A	acetyl-CoA acyltransferase 2	VMH	18391478 HMDB00847
MMDBr0005197	5-Dodecenoyl Coenzyme A	3-Decenoyl Coenzyme A	acetyl-CoA acyltransferase 2	VMH	20195903 20490924 17143551
MMDBr0005205	Lauroyl-CoA	Decanoyl-CoA (N-C10:0CoA)	acetyl-CoA acyltransferase 2	VMH	20195903 20490924 17143551
MMDBr0005207	Lauroyl-CoA	(S)-3-Hydroxydodecanoyl-CoA	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	1730577 HMDB00387
MMDBr0005213	Tridecanoyl Coenzyme A	Undecanoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	18391478
MMDBr0005214	7-Tetradecenoyl Coenzyme A	5-Dodecenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005216	7-Tetradecenoyl Coenzyme A	3-Hydroxy Tetradecenoyl-7 Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	21281499
MMDBr0005217	5,8,11-Tetradecatrienoyl Coenzyme A	3,6,9-Dodecatrienoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005219	Tetradecanoyl-CoA	Lauroyl-CoA	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005221	Tetradecanoyl-CoA	(S)-3-Hydroxytetradecanoyl-CoA	acyl-CoA dehydrogenase, very long chain	VMH	11427448
MMDBr0005225	Pentadecanoyl Coenzyme A	Tridecanoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	18391478
MMDBr0005228	Palmitoleyl-CoA	7-Tetradecenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005230	7,10-Hexadecadienoyl Coenzyme A	5,8-Tetradecadienoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005231	Trans7,10-Hexadecadienoyl Coenzyme A	3-Hydroxy Trans7,10-Hexadecadienoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	21281499
MMDBr0005233	7,10,13-Hexadecatrienoyl Coenzyme A	5,8,11-Tetradecatrienoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005234	4,7,10-Hexadecatrienoyl Coenzyme A	2,4,7,10-Hexadecatetraenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	17374501
MMDBr0005242	4,7,10,13-Hexadecatetraenoyl Coenzyme A	2,4,7,10,13-Hexadecapentaenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	17374501
MMDBr0005250	Palmityl-CoA	Tetradecanoyl-CoA	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005252	Palmityl-CoA	(S)-3-Hydroxyhexadecanoyl-CoA	acyl-CoA dehydrogenase, very long chain	VMH	9510849 10657369
MMDBr0005256	Heptadecanoyl Coenzyme A	Pentadecanoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	18391478
MMDBr0005257	11-Octadecenoyl Coenzyme A	Palmitoleyl-CoA	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005259	Octadecenoyl Coenzyme A	3-Hydroxyoctadecenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	9510849
MMDBr0005260	Linoleoyl-CoA	7,10-Hexadecadienoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH
MMDBr0005261	Gamma-linolenoyl-CoA	4,7,10-Hexadecatrienoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005262	Alpha-Linolenoyl-CoA	7,10,13-Hexadecatrienoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005265	Stearidonoyl CoA	4,7,10,13-Hexadecatetraenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005268	Stearoyl-CoA	(3R)-3-hydroxy-stearoyl-CoA	Not Available	VMH	11751554
MMDBr0005271	5,8,11,14,17-Eicosapentenoyl Coenzyme A	3,6,9,12,15-Octadecapentenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	20195903 20490924 17143551
MMDBr0005273	Docosa-4,7,10,13,16-pentaenoyl CoA	2,4,7,10,13,16-Docosahexenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	17374501
MMDBr0005280	Cervonyl Coenzyme A	2,4,7,10,13,16,19-Docosaheptenoyl Coenzyme A	acyl-CoA dehydrogenase, very long chain	VMH	17374501
MMDBr0005291	Pentanoyl Coenzyme A	Propionyl-CoA	acetyl-CoA acyltransferase 2	VMH	10200137
MMDBr0005299	Hexanoyl-CoA	Butyryl-CoA	acetyl-CoA acyltransferase 2	VMH	20195903 20490924 17143551
MMDBr0005302	Heptanoyl Coenzyme A	Pentanoyl Coenzyme A	acetyl-CoA acyltransferase 2	VMH	18391478
MMDBr0005303	5-Octenoyl Coenzyme A	3-Hexenoyl Coenzyme A	acetyl-CoA acyltransferase 2	VMH	20195903 20490924 17143551
MMDBr0005305	Octanoyl-CoA	Hexanoyl-CoA	acetyl-CoA acyltransferase 2	VMH	20195903 20490924 17143551
MMDBr0005308	4,8 Dimethylnonanoyl Coenzyme A	2,6-Dimethylheptanoyl-CoA	Not Available	VMH	9469587 HMDB06258 9714723 11591435
MMDBr0005309	Nonanoyl Coenzyme A	Heptanoyl Coenzyme A	acetyl-CoA acyltransferase 2	VMH	18391478 HMDB00666
MMDBr0005314	Trans4Decenoyl Coenzyme A	Cis2Trans4Decadienoyl Coenzyme A	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	VMH	15337167
MMDBr0005471	Ubiquinone-1	Ubiquinol-10	electron-transfer-flavoprotein, alpha polypeptide	VMH	30371894
MMDBr0005483	Glycerol 3-phosphate	Dihydroxyacetone phosphate	Not Available	VMH	30371894
MMDBr0007012	Glutaryl-CoA	Glutaconoyl-CoA	Not Available	VMH	30371894
MMDBr0007032	Glutaryl-CoA	Crotonoyl-CoA	Not Available	VMH	30371894
MMDBr0007198	(S)-malate(2-)	Oxalacetic acid	Not Available	VMH	30371894
MMDBr0007212	4-Hydroxyproline	Pyrroline hydroxycarboxylic acid	Not Available	VMH	30371894
MMDBr0007544	L-Proline	L-D-1-Pyrroline-5-carboxylic acid	Not Available	VMH; KEGG	30371894
MMDBr0007573	Succinic acid	Fumaric acid	Not Available	VMH	30371894
MMDBr0007818	Glycerol 3-phosphate	Dihydroxyacetone phosphate	Not Available	VMH	30371894
MMDBr0008118	Gluconic acid	2-Dehydro-D-gluconate	Not Available	VMH	30371894
MMDBr0008126	dUMP	5-Thymidylic acid	Not Available	VMH	30371894
MMDBr0008316	Isovaleryl-CoA	3-Methylcrotonyl-CoA	Not Available	VMH	30371894
MMDBr0008488	2-Methylbutyryl-CoA	Tiglyl-CoA	Not Available	VMH	30371894
MMDBr0008489	Isobutyryl-CoA	Methacrylyl-CoA	Not Available	VMH	30371894
MMDBr0008495	L-Pipecolic acid	2,3,4,5-Tetrahydro-2-pyridinecarboxylic acid	Not Available	VMH	30371894
MMDBr0008525	(S)-malate(2-)	Oxalacetic acid	Not Available	VMH	30371894
MMDBr0008527	Glycerol 3-phosphate	Dihydroxyacetone phosphate	Not Available	VMH	30371894
MMDBr0008534	Butyryl-CoA	Crotonoyl-CoA	Not Available	VMH	30371894
MMDBr0008536	Succinic acid	Fumaric acid	Not Available	VMH	30371894
MMDBr0008610	Glutaryl-CoA	Trans-Delta-2-Glutaryl Coenzyme A	Not Available	VMH	30371894
MMDBr0008617	Glutaryl-CoA	Glutaconyl Coenzyme A	Not Available	VMH	30371894
MMDBr0008832	Heptadecanoyl Coenzyme A	Trans-Delta-2-Heptadecanoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	30371894
MMDBr0009312	Dihydroxyacetone phosphate	Glycerol 3-phosphate	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	VMH; KEGG	30371894
MMDBr0009370	Oxoglutaric acid	2-Hydroxyglutarate	L-2-hydroxyglutarate dehydrogenase	VMH; KEGG	30371894
MMDBr0009480	20-Carboxy-leukotriene B4	18-Carboxy Dinor Leukotriene B4	Not Available	VMH	30371894
MMDBr0010040	Docosanoyl-CoA	trans-docos-2-enoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010044	Eicosanoyl-CoA	(2E)-eicosenoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010048	Stearoyl-CoA	Trans-Octadec-2-enoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010052	Palmityl-CoA	(2E)-Hexadecenoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010053	Tetradecanoyl-CoA	(2E)-Tetradecenoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010054	Lauroyl-CoA	(2E)-Dodecenoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010055	Decanoyl-CoA (N-C10:0CoA)	(2E)-Decenoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010056	Octanoyl-CoA	(2E)-Octenoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010057	Hexanoyl-CoA	trans-2-Hexenoyl-CoA	acyl-CoA dehydrogenase, short/branched chain	VMH	30371894
MMDBr0010058	Heneicosanoyl Coenzyme A	(2E)-Heneicosenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010062	Nonadecanoyl Coenzyme A	(2E)-Nonadecenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010066	Heptadecanoyl Coenzyme A	(2E)-Heptadecenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010070	Pentadecanoyl Coenzyme A	(2E)-Pentadecenoyl-CoA	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010074	Tridecanoyl-CoA	(2E)-Tridecenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010078	Undecanoyl-CoA	(2E)-Undecenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010082	Nonanoyl-CoA	(2E)-Nonenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010086	Heptanoyl-CoA	(2E)-Heptenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010090	Pentanoyl-CoA	(2E)-Pentenoyl-CoA	acyl-CoA dehydrogenase, short/branched chain	VMH	30371894
MMDBr0010094	13Z-docosenoyl-CoA	Trans,Cis-2,13-Docosadienoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010098	11Z-Eicosenoyl Coenzyme A	Trans,Cis-2,11-Eicosadienoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010103	7Z-Hexadecenoyl Coenzyme A	Trans,Cis-Hexadeca-2,7-Dienoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010107	5Z-tetradecenoyl-CoA	Trans,Cis-Myristo-2,5-Dienoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010111	13Z-Eicosenoyl Coenzyme A	Trans,Cis-2,13-Eicosadienoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010115	11Z-Octadecenoyl Coenzyme A	Trans,Cis-Octadeca-2,11-Dienoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010120	cis,cis-3,6-Dodecadienoyl-CoA	trans,cis-Lauro-2,6-dienoyl-CoA	enoyl CoA hydratase 1, peroxisomal	VMH	30371894
MMDBr0010162	10Z-Heptadecenoyl Coenzyme A	Propionyl-CoA	Not Available	VMH	30371894
MMDBr0010163	9Z-Heptadecenoyl Coenzyme A	Propionyl-CoA	Not Available	VMH	30371894
MMDBr0010184	8Z,11Z,14Z-eicosatrienoyl-CoA	Trans-2-Cis,Cis,Cis-8,11,14-Eicosatetraenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010188	Gamma-linolenoyl-CoA	2E,6Z,9Z,12Z-Octadecatetraenoyl Coenzyme A	acyl-CoA dehydrogenase family, member 9	VMH	30371894
MMDBr0010200	4,8 Dimethylnonanoyl Coenzyme A	4(R),8-Dimethyl-Trans-2-Nonenoyl Coenzyme A	acyl-CoA dehydrogenase, long chain	VMH	30371894
MMDBr0010983	Butyryl-CoA	Crotonoyl-CoA	Not Available	VMH	30371894
MMDBr0010989	4-Hydroxyproline	Pyrroline hydroxycarboxylic acid	Not Available	VMH	30371894
MMDBr0011025	Oxoglutaric acid	Succinic acid	Not Available	VMH	30371894

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference
Anorexia nervosa		Association	Human Blood	HMDB	10197568

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria/Eubacteria	Bacteroidetes	127	Human stool; Human ; Human feces; Human appendix biopsy; Human saliva; Human gastric fluid; Human urine; Human subgingival plaque; Human supragingival plaque	Indirect association between microbiota composition and metabolites measured in host biospecimen; Metabolic reconstruction
Bacteria/Eubacteria	Firmicutes	379	Human stool; Human ; Human urine; Human feces; Human pleural fluid plaque; Pig ; Human sputum; Human subgingival plaque; Human saliva; Human mucosa; Human supragingival plaque; Cattle	Indirect association between microbiota composition and metabolites measured in host biospecimen; Metabolic reconstruction
Bacteria/Eubacteria	Actinobacteria	120	Human vaginal fluid; Human feces; Human sputum; Human bronchial brush; Human nasopharyngeal swab; Human pleural fluid plaque; Human dental plaque; Human ; Human mucosa; Human supragingival plaque; Human subgingival plaque; Human saliva; Cattle	Indirect association between microbiota composition and metabolites measured in host biospecimen; Metabolic reconstruction
Bacteria/Eubacteria	Proteobacteria	227	Human feces; Human sputum; Human ; Human unknown; Pig ; Human pleural fluid plaque; Human dental plaque; Human nasal swab; Human stool; Human feces; pleural fluid plaque; bal; Human subgingival plaque	Metabolic reconstruction
Bacteria	Actinobacteria	21	Human vaginal fluid; Human feces; Human sputum; Human bronchial brush; Human nasopharyngeal swab; Human pleural fluid plaque; Human dental plaque; Human ; Human mucosa; Human supragingival plaque; Human subgingival plaque; Human saliva; Cattle	Indirect association between microbiota composition and metabolites measured in host biospecimen; Metabolic reconstruction
Bacteria/Eubacteria	Verrucomicrobia	1	Human ; Human feces	Metabolic reconstruction
Bacteria/Eubacteria	Synergistetes	3	Human feces	Metabolic reconstruction
Bacteria	Firmicutes	29	Human stool; Human ; Human urine; Human feces; Human pleural fluid plaque; Pig ; Human sputum; Human subgingival plaque; Human saliva; Human mucosa; Human supragingival plaque; Cattle	Indirect association between microbiota composition and metabolites measured in host biospecimen; Metabolic reconstruction
Bacteria	Proteobacteria	15	Human feces; Human sputum; Human ; Human unknown; Pig ; Human pleural fluid plaque; Human dental plaque; Human nasal swab; Human stool; Human feces; pleural fluid plaque; bal; Human subgingival plaque	Metabolic reconstruction
Bacteria/Eubacteria	Spirochaetes	1	Human feces	Metabolic reconstruction
Archaea	Thaumarchaeota	1		Metabolic reconstruction
Bacteria/Eubacteria	Fusobacteria	20	Human feces; Human	Metabolic reconstruction
Archaea	Euryarchaeota	5		Metabolic reconstruction
Bacteria	Candidatus melainabacteria	1	Human feces	Metabolic reconstruction
Bacteria/Eubacteria	Tenericutes	7	Human feces; Human	Metabolic reconstruction
Bacteria/Eubacteria	Planctomycetes	1	Human feces	Metabolic reconstruction
Archaea	Crenarchaeota	1		Metabolic reconstruction
Bacteria	Synergistetes	1	Human feces	Metabolic reconstruction
Eukaryota/Fungi	Ascomycota	6	Human feces; Human saliva	Unknown
Bacteria	nah	1
Archaea/Archaea	Euryarchaeota	55		Metabolic reconstruction
Archaea/Archaea	Korarchaeota	1
Bacteria/Eubacteria	Deinococcus-thermus	1
Eukaryota/Fungi	Basidiomycota	1

Exposure Sources

Source Type	Activity	Data Source	Reference
Drugs	Antimicrobial	U.S. Environmental Protection Agency	CompTox
Cosmetics	Not Available	U.S. Environmental Protection Agency	CompTox
Domestics	Not Available	U.S. Environmental Protection Agency	CompTox
Cosmetics	Not Available	U.S. Environmental Protection Agency	CompTox

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified									HMDB
Human Blood	Detected and Quantified	0.048	0.023			uM	Adolescent (13-18 years old)	Female	Anorexia nervosa	HMDB	10197568
Human Blood	Detected and Quantified	0.061		0.044	0.078	uM	Adult (>18 years old)	Female	Normal	HMDB	18230968
Human Blood	Detected and Quantified	0.075		0.056	0.097	uM	Adult (>18 years old)	Both	Normal	HMDB	12194936
Human Blood	Detected and Quantified	0.078	0.054			uM	Adolescent (13-18 years old)	Female	Normal	HMDB	10197568
Human Erythrocyte	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Liver	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Placenta	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Skeletal muscle	Detected but not Quantified						Not Specified	Not Specified	Normal	HMDB	34986597
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	27543620
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	25037050
Human Feces	Detected but not Quantified						Adult (>18 years old)	Both	Normal	HMDB	29808030

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Kodentsova VM, Vrzhesinskaia OA, Alekseeva IA, Spirichev VB: [Comparison of biochemical criteria for supplying the human body with riboflavin]. Vopr Med Khim. 1991 Sep-Oct;37(5):76-9. [PubMed:1759408 ]
Van Binsbergen CJ, Odink J, Van den Berg H, Koppeschaar H, Coelingh Bennink HJ: Nutritional status in anorexia nervosa: clinical chemistry, vitamins, iron and zinc. Eur J Clin Nutr. 1988 Nov;42(11):929-37. [PubMed:3074921 ]
Cimino JA, Noto RA, Fusco CL, Cooperman JM: Riboflavin metabolism in the hypothyroid newborn. Am J Clin Nutr. 1988 Mar;47(3):481-3. doi: 10.1093/ajcn/47.3.481. [PubMed:3348160 ]
Lopez-Anaya A, Mayersohn M: Quantification of riboflavin, riboflavin 5'-phosphate and flavin adenine dinucleotide in plasma and urine by high-performance liquid chromatography. J Chromatogr. 1987 Dec 25;423:105-13. doi: 10.1016/0378-4347(87)80332-8. [PubMed:3443641 ]
Cimino JA, Jhangiani S, Schwartz E, Cooperman JM: Riboflavin metabolism in the hypothyroid human adult. Proc Soc Exp Biol Med. 1987 Feb;184(2):151-3. doi: 10.3181/00379727-184-42459. [PubMed:3809170 ]
Flatz G, Simmersbach F: Flavin adenine dinucleotide concentration in erythrocytes with normal and deficient glucose-6-phosphate dehydrogenase. Klin Wochenschr. 1970 Sep 1;48(17):1071-2. doi: 10.1007/BF01497217. [PubMed:5523465 ]
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Showing metabocard for FAD (MMDBc0000567)

MOL for #<Metabolite:0x00007f3e111366d0>

3D MOL for #<Metabolite:0x00007f3e111366d0>

3D SDF for #<Metabolite:0x00007f3e111366d0>

3D-SDF for #<Metabolite:0x00007f3e111366d0>

PDB for #<Metabolite:0x00007f3e111366d0>

3D PDB for #<Metabolite:0x00007f3e111366d0>

SMILES for #<Metabolite:0x00007f3e111366d0>

INCHI for #<Metabolite:0x00007f3e111366d0>

Structure for #<Metabolite:0x00007f3e111366d0>

3D Structure for #<Metabolite:0x00007f3e111366d0>